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  • afobazol 0,01 N60 pills

The composition of морфолиноэтилтиоэтоксибензимидазола dihydrochloride 10 mg excipients: potato starch, cellulose microcrystalline, lactose, povidone, magnesium stearate. Pharmacological action of Afobazol - derived 2-mercaptobenzimidazole, selective anxiolytic, not belonging to the class of benzodiazepine receptor agonists. Prevents the development membranosvazannah changes in GABA-a receptor. The drug has anxiolytic activity with an activating component, not accompanied by gipnosedativny effects (sedative effect is revealed in doses in 40-50 times the ED50 for anxiolytic action). The drug lacks muscle relaxant properties, negative effect on memory and attention. If the drug is not formed drug dependence and not developing the syndrome. The effect of the drug is realized mainly in the form of a combination of anxiolytic (antianxiety) and easily stimulating (activating) effects. Reducing or eliminating anxiety (concern, foreboding, fear, irritability), tension (fearfulness, tearfulness, anxiety, inability to relax, insomnia, fear) and, hence, somatic (muscular, sensory, cardiovascular, respiratory, gastrointestinal symptoms), vegetative (dry mouth, sweating, dizziness), cognitive (difficulty concentrating, impaired memory) violations observed by 5-7 days of treatment Afobazol. The maximum effect is achieved by the end of 4 weeks of treatment and stored in politematicheskaya period averaging 1-2 weeks. Especially shows the use of the drug in individuals with predominantly asthenic personality traits in the form of alarming suspiciousness, insecurity, increased vulnerability and emotional lability, tendency to emotional stress reactions. Afobazol is non-toxic (LD50 in rats is 1.1 g at ED50 1 mg). Pharmacokinetics Absorption C max is 0.13±0.073 µg/ml. Distribution of the Average holding time drug in the body - 1.6±0.86 h. Rapidly distributed in well-vascularized organs. The elimination T1/2 is 0.82 h

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afobazol 0,01 N60 pills

  • Product Code: 144
  • Availability: In Stock
  • $22.00