• Acyclovir 0,2 N25 tabs

Pharmaceutical form Ointment for external use 5% white or almost white; tolerance characteristic odour. Composition 100 g acyclovir 5 g excipients: propylene glycol 40 g, vaseline - 12.5 g vaseline oil - 7.5 g, wax emulsion 5 g, macrogol (polyethylene oxide 1500) - 1 g, purified water up to 100 g Pharmacological action Antiviral drug - a synthetic nucleoside analogue of thymidine. In infected cells containing viral timidinkinaza, is the phosphorylation and turning into acyclovir monophosphate. Under the influence called guanylate cyclase acyclovir monophosphate is converted to the diphosphate and under the influence of several cellular enzymes to the triphosphate. High selectivity and low toxicity to humans due to the lack of the necessary enzyme for the formation of acyclovir triphosphate in intact cells of the microorganism. Acyclovir triphosphate, "embedding" in the synthesized virus DNA, blocks reproduction of the virus. Specificity and very high selectivity of action is also due to its preferential accumulation in the cells infected with the herpes virus. Highly active against the virus Herpes simplex 1 and 2, the virus that causes chickenpox and shingles (Varicella zoster); Epstein-Barr. Moderately active against cytomegalovirus. Pharmacokinetics When applied to intact skin: absorption is minimal; not detected in blood and urine. On the affected skin: absorption is moderate; in patients with normal renal function concentration in the serum is up to 0.28 mcg/ml in patients with chronic renal failure (CRF) - up to 0.78 µg/ml. Excreted by the kidneys (up to 9.4% of the daily dose).

Write a review

Note: HTML is not translated!
    Bad           Good

Acyclovir 0,2 N25 tabs

  • Product Code: 70
  • Availability: In Stock
  • $9.90

Tags: Acyclovir 0, 2 N25 tabs